







🐾 Clear ears, happy pets—because they deserve the best care!
Zymox Advanced Formula Otic Plus is a vet-recommended enzymatic ear solution for dogs and cats that combines the LP3 Enzyme System with 1% Hydrocortisone to effectively clear biofilms, soothe itching, and reduce inflammation. Its gentle, no-pre-cleaning formula ensures easy application and fast relief from common ear irritations, making it an essential part of any pet care routine.






































| Customer Reviews | 4.7 out of 5 stars 13,874 Reviews |
A**R
Cleared Up My Dog’s Ear Flare-Up Fast
My dog occasionally gets ear irritation — shaking his head, scratching, and redness inside the ear. It’s stressful to watch, and I always want to address it quickly before it turns into something worse. This Zymox Otic Plus has been a lifesaver for us. What I like is that it contains 1% hydrocortisone, which helps calm inflammation and itching. Within a couple of days, I noticed he wasn’t shaking his head as much, and the redness started to look better. It seems to soothe pretty quickly. The dropper tip makes it easy to apply, and I gently massage the base of the ear as directed. It’s simple to use and doesn’t require pre-cleaning, which makes the process much less stressful for both of us. Of course, for severe or recurring infections I would still consult a vet, but for mild flare-ups and irritation, this has worked really well in our experience. If your dog or cat deals with occasional ear redness or itching, this is definitely worth having in your pet care kit. It’s effective, easy to apply, and brought noticeable relief within a few days.
J**I
Most Effective Ear Treatment Vet Recommended
I use this for my pups whenever I notice scratching at their ears. It is a Godsend. Interestingly, while at the vet in the last exam, I noticed a large bottle of Zy on the countertop. The Vet said it was very effective, and what they use for treatment. Sometimes they only need it a few days to take the redness and itching away. I can see relief in Julia as soon as I treat her. This product comes always within two days of the order, never an issue, great product, my pups appreciate.
V**E
Effective Relief for Dog's Itchy Ears
Definitely 5 stars because it worked exactly as advertised. My dog was dealing with red, itchy ears, and this formula cleared up the irritation completely without the need for an expensive vet visit. It was very easy to use, especially since it doesn't require pre-cleaning the ears beforehand, which made the process much easier on my dog. Within a few days, the redness was gone and she stopped scratching. It’s a reliable, effective product that saved us a lot of time and money, and I’ll definitely be keeping it on hand for any future ear issues.
A**R
AMAZING PRODUCT!!
My pups ear was red and had some gunk in it. Took them to the vet for a routine visit and was told they had left and right ear infections. They also charged us for a prescription ear drops that had to be put in twice a day. The prescription only made my pups ear much worse. I used this product as soon as it was delivered in the morning. My pups was showing signs of relief within 20 minutes and the redness was completely gone before end of day. Thanks for making an affordable product that actually works. I'm recommending ZYMOX to everyone with a dog or cat, even the vet office. Does not smell and it's very easy to apply. If your pet has gunk build up, it will slide out so have soft clean cloth or tissue.
T**T
Beats the itch
Helped my dog a great deal
T**L
Great product
This works great and I can tell my dog feels so much better after use. On day 5-7 it turns into a thing layer that peels off all the grime.
G**K
Excellent ear medication!
The best stuff for dogs with ear issues. Starts working right away and dogs ears are feeling better in the first day of use.
B**M
Works!
Resolved completely, I hope the issue doesn't return but so far so good!!! It's been a week and his ears still look clean. I want to start by saying I didn't know what was wrong with my babies ears. I have a 6 month old kitten I adopted that had very dark waxy and dirty ears. I suspected yeast or mites. I treated for 8 days although the issue looked fully resolved on day 6. Afterwards I cleaned his ears one last time with Veterinary formula ear cleaner also sold on Amazon. He was not scratching his ears excessively but I checked his ears anyway and noticed how dirty they were and I'm shocked he wasn't scratching because they were filthy and so waxy and wet/ yeasty looking. Cats have clean ears naturally so I knew it wasn't normal. The kitten was tolerating treatment surprisingly well especially for the Zymox plus because it's a little thicker. The ear cleaner I used once after completing the Zymox he didn't like near as much but it's quite runny. His ears are really clean. In case there's an issue with mites, I plan on using on and off for a month with skipping a week between each treatment since eggs can hatch after a week or two. The vet said this would be safe to use for a month but if the issue returns I'll take my kitten to the vet. So far so good. I can't believe the amount of wax expelled from his ears.. I would purchase again.
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