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🚿 Keep your drains flowing like a pro—no clogs, no stress!
Zep Drain Defense is a professional-strength, enzyme-based liquid remover designed to break down and eliminate years of pipe buildup. Safe for PVC and most septic systems, it restores flow and prevents clogs for up to 21 months with regular use. Ideal for sinks, garbage disposals, tubs, RVs, and grease traps, this eco-friendly formula decomposes into harmless CO2, minerals, and water, ensuring powerful yet safe drain maintenance.























| ASIN | B001AZQR9C |
| Best Sellers Rank | #1,060 in Industrial & Scientific ( See Top 100 in Industrial & Scientific ) #6 in Commercial Drain Openers #21 in Chemical Drain Openers |
| Brand | Zep |
| Brand Name | Zep |
| Customer Reviews | 4.0 out of 5 stars 3,471 Reviews |
| Global Trade Identification Number | 00021709011302, 00021709600629, 00070048027161, 20021709600623, 40021709600627 |
| Included Components | Concentrate |
| Item Form | bottle |
| Item Type Name | Zep Drain Defense Pipe Build-Up Remover - 64 Ounces - ZLDC648 - Professional Strength Liquid Pipe Build Up Remover,GREEN |
| Item Weight | 1.9 Kilograms |
| Liquid Volume | 64 Fluid Ounces |
| Manufacturer | ZEP COMMERCIAL PRODUCTS |
| Model Number | ZLDC648 |
| Number of Items | 1 |
| Part Number | ZLDC648 |
| Product Benefits | Eliminates clogs, restores flow, and provides 21 months of drain protection |
| Scent | Unscented |
| State of Matter | Liquid |
| State of matter | Liquid |
| UPC | 021709600629 070048027161 021709011302 |
| Unit Count | 64.0 Fluid Ounces |
| Warranty Description | Warranty |
C**T
BAD REVIEWS, BECAUSE CUSTOMER NOT USEING CORRECTLY
THIS IS NOT A CLOG REMOVER..ITS ADDED TO YOUR SYSTEM FOR PIPES CLEANED OUT BULID UP OVER TIME.. IT HAS ENZYMES TO BREAK DOWN AND KEEPS PIPES CLEAN.. ITS A TREATMENT OVER TIME WORKS EXCELLLENT.. RUN OR ADD HOT WATER, THEN ADD TWO CUPS ,YES TWO CUPS,THEN ADD A ONE CUP OF HOT WATER..TO WASH OUT OF TRAP.. LET IN SET FOR AROUND 8 HOURS FOR BEST RESULTS.. DO ONCE A MONTH...
J**Y
WORKS -- all that matters
Zep is my 'go to' for a clogged toilet. Might not work on first try ... or second ... even third ... BUT it eventually works and isn't as 'messy' or gross as using a snake. ~half bottle, 12 hour wait, HOT water chaser for 15 minutes ... flush *use when the house has multiple toilets because the clogged toilet will be unavailable **IF you need immediate results, use a snake or call a plumber
S**6
Works on everything if used in main drain
So I had an upstairs toilet issue. When using the shower or the 2 sinks in the main bath, the toilet will make a gargle noise, backup but not over flow, and the water in the toilet will be up to the rim for almost 5 hours before it flushed. Even if I flush the toilet, the same would happen. After reading reviews and leaning on my understanding of chemistry and cooking. I realized that the main drain in my townhome ran through my upstairs shower. So I removed the shower drain cover and poured the entire bottle of Zep down the drain. I waited 5 hours. Mostly because I had others things to do. I then heated water in a midsize pot until it started to boil. Once it began to boil I left the cover on the pot but let it sit with the heat off. I then (with oven gloves) carried the cover pot to the bathroom and slowly poured the hot water down the shower. I waited ...some odd hours later I heard something like a demon from h*ll coming from my upstairs bathroom. I don't know why I ran towards it. Every black person knows to run in the opposite direction in scary movies. But I ran to the noise. When I arrived the floor of my shower was covered in what I thought was BM but later realized it was mud/ dirt and Lord knows what ever. There was no odor. I then tested the toilet because I noticed it was back at normal level in the bowl. The toilet flushed with gusto and didn't make a noise or back up when using the sinks or shower. I then used a half of gallon of Clorox to clean my shower with a long arm brush & sponge. Total resolve time : 12-16 hours
R**L
Great Unclogger!
This is the only product we will use for unplugging drains. We use it periodically on the kitchen drain bc we use minimal water to wash waste off dishes. Eventually the drain will go slow. We leave it in overnight. Flush it out with a bucket of hot water in the am. Always works!
A**Y
DOES NOT WORK
DOES NOT WORK. Literally had to use the entire thing a little at a time because it wouldn’t work at all. Doesn’t drain any differently and I just wasted my time. It’s a waste of money. Do not buy. It’s better to just pay a little extra for Draino or something.
N**L
Good ish
Good but also requires more then instructed
E**L
Best stuff for hard water issues
Best stuff for clearing our drains. used other stuff for our hard water deposits and our bathroom drain would start clogging up at least every 2 months. Been using this stuff for over 2 years now and not one issue.
K**N
unexpected solution to longstanding problems
I thought that my sink's water supply had magically gained an on again off again sulfur smell. Turns out, there was just something growing in the drain, and that water was disturbing it, causing the sulfur smell to waft upward. Leaving this in the drain for a few hours fixed that problem. Throwing this down the kitchen sink drain may have killed off a gnat issue as well. I'd frequently wake up to two or three gnats hanging out near the kitchen sink. But after a treatment of this stuff, no gnats. ...or whatever the tiny winged bugs were. They were slow enough to easily swat / squish manually.
A**T
Saved me money on calling a plumber
I don’t usually write reviews, but after battling my kitchen sink for days, I feel like I just won a war. Plungers? Useless. Every other drain cleaner I could find? Nope. Even my auger failed me. I was this close to calling a plumber, but I figured I’d take one last shot with this product. And guess what? It actually worked! Took a few rounds—my clog was determined—but I could see progress each time, my sink slowly admitting defeat. Now that my pipes are back in working order, I’m not taking any chances and ordered another bottle for monthly maintenance cause there is no way in hell I'm going through all that again.
4**R
The best drain care liquid ever!
Take my word for it. You can't see the build up inside your drains and pipes. Don't use harsh chemicals. They will destroy you pipes. Use Zep. Monthly, regular usage of Zep will ensure that your pipes stay clog free. Eliminate costly visits from the plumber. Use Zep today!
D**W
Good for drain monthly maintenance.
purchased to use on a monthly basis to prevent drain enzyme build-up.. I live in a building built in the 70's and the plumbing system is not great so hopefully monthly doses of Zep will help.
D**S
Plugged a slow drain
Is it me or does my slow drain always plug when I put drain cleaner in it?
J**Y
It works
Good quality and great for my plastic pipes since it is not corrosive. It provided better results than Draino for my metal pipes as well.
Trustpilot
2 weeks ago
2 months ago