Question 1

If this item is not using the faster and most recent or updated chipset is there one that is by this manufacturer and if not then by another one?

Accepted Answer

a number of Reviews here beginning 9-2022 show THIS product's box is updated model TBU401E.  (with "E")
the box states the included cable is Thunderbolt 3.
it drops the false claim printed on the earlier TBU401 box of "USB 4.0".

-----(  newer TBU401E  )-----
https://m.media-amazon.com/images/I/41n8r+Qr+4L.jpg
https://m.media-amazon.com/images/I/41vqV5YTrjL.jpg
https://m.media-amazon.com/images/I/61iyaANm7qL.jpg
https://m.media-amazon.com/images/I/61TKeFrG5NL.jpg

-----( original TBU401 )-----
https://m.media-amazon.com/images/I/81-0pILAsAL.jpg

it seems like all brand enclosures boasting "40Gbps Thunderbolt4 / USB4" are JHL7440 chipset based.
the JHL7440 is actually Thunderbolt3, (not TB4 or USB4), which actually produces only 22Gbps data transfer.
(per Intel, 18Gbps of 40Gbps is reserved for Displayport video).
they also do not support USB Gen 2x2 20Gbps mandatory with USB4.  only USB 3.1 10Gbps.

there's no telling which exact model ACASIS (or anybody else) is shipping at this very moment.
none can possibly transfer 40Gbps - that's 5000 MB/s.  they all get approx half that.
none are USB4 - their USB interface is only USB 3.1.
that's all there is to it.  the ads are all consistently deceptive and untruthful.
and most Answerers in the Q&A only help compound the fraud.
.

Question 2

Does this enclosure support nvme 4.0 or only 3.0? will using a 4.0 capable drive provide speed improvements with this enclosure?

Accepted Answer

No, you most likely will see no difference as others answered partially but not directly. You are bottlenecked by 1- Thunderbolt 3, which theoretically can handle 40Gbs/5,000MBps, but in the real world in my experience tops at 3,500~ish. 2- Various other parameters such as cable quality, NVME drive technologies, SLC, TLC, QLC, VNAND, etc. 
My suggestion: Buy the BEST NVME 3.0 you can, with the largest DRAM or SLC cache, AND make sure that below that cache it has VNAND instead of regular NAND. Keep an eye on too high densities as well. SLC is faster than TLC which is faster than QLC… Best. R.

Question 3

Hi, does this drive run a 10gb if i hook it up to a regular usb 3.2 gen 2 port?  thanks!

Accepted Answer

USB 3.2 Gen 2 max speed is 10 Gbps. The USB port cannot get faster speed, just because a faster devices was connected to that port.

Question 4

What is the difference between tbu401 and tbu401e?

Accepted Answer

review photos show the models are marked differently on their aluminum bodies.

Model: TBU401
Product: USB 4.0 SSD Enclosure
[plug] USB 4.0

https://m.media-amazon.com/images/I/81CDPDhXKwL.jpg
https://m.media-amazon.com/images/I/81T4g-iTRYL.jpg
https://m.media-amazon.com/images/I/81-0pILAsAL.jpg

Model: TBU401E
Product: NVMe SSD Enclosure
[plug] Type-C 40Gbps

https://m.media-amazon.com/images/I/61TnyPjrIkL.jpg
https://m.media-amazon.com/images/I/51vaS5DXQTL.jpg
https://m.media-amazon.com/images/I/51TWhmCtRpL.jpg
https://m.media-amazon.com/images/I/61TKeFrG5NL.jpg
.

ASIN	B0BB74BQVN
Best Sellers Rank	#205 in Enclosures
Brand	ACASIS
Built-In Media	enclosure
Color	Silver
Compatible Devices	mac mini, macbook air, macbook pro
Customer Reviews	4.5 4.5 out of 5 stars (689)
Data Transfer Rate	2300 megabits_per_second
Enclosure Material	Aluminum
Hard Disk Form Factor	22 millimeters
Hardware Interface	Thunderbolt
Hardware Platform	Linux, Mac, PC
Item Dimensions L x W x H	4.09"L x 2.13"W x 0.63"H
Item Weight	137 g
Manufacturer	ACASIS
Memory Storage Capacity	8 TB
Mfr Part Number	TBU-401
Model Number	TBU-401
Supported Devices Quantity	1
Warranty Description	1 YEAR

ACASIS 40Gbps M.2 NVMe SSD Enclosure with Aluminum Housing, No Noise M.2 Enclosure Compatible Thunderbolt5/4/3/USB4/3.2/3.1/3.0/2.0,NVMe ssd Enclosure for MacBook Air /Pro Support 2280/2260/2242/2230

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