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🐾 Stay ahead of pests—because your big dog deserves big protection!
K9 Advantix II Extra Large Dog is a vet-recommended, topical flea and tick treatment designed for dogs over 55 lbs. It kills and repels fleas, ticks, mosquitoes, biting flies, and lice within 12 hours of application. The formula is fragrance-free, waterproof after 24 hours, and provides 30 days of continuous protection. Available over the counter, it offers an easy, fast, and effective monthly solution to keep your dog comfortable and pest-free.













| ASIN | B07NX2VWYC |
| Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen |
| Age Range Description | 7 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #235 in Pet Supplies ( See Top 100 in Pet Supplies ) #4 in Dog Flea Drops |
| Brand | K9 Advantix |
| Brand Name | K9 Advantix |
| Customer Reviews | 4.5 out of 5 stars 48,522 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089114945 |
| Item Form | Topical |
| Item Type Name | Topical |
| Item Volume | 4 Milliliters |
| Item Weight | 0.05 Pounds |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 90204386 |
| Model Number | 90204386 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089114945 |
| Unit Count | 1 Count |
| Volume | 4 Milliliters |
I**P
Great product for small dogs
My mom lives out in the rural sticks. Her herd of small dogs has thrived out there for years, usually with no attention paid to fleas and whatnot until it becomes a problem. The solution was always a flea bath, maybe some Adams spray, and they are good to go until the next time. I'm not sure which is most to blame, but between the recent hot weather and the addition of ~20 chickens to her zoo (which in turn brings in unknown numbers of flea and tick covered rodents to get into the chicken feed and predators to try to get chickens), the fleas are thriving outdoors. ....and after many years of inconsistent flea protection they were thriving on her dogs, who primarily live indoors. Now, I am working to combat an active flea infestation in her house. The first application of this stuff has the dogs happier and not scratching as much. With the help of some 1ml oral syringes, I was able to turn one XL dog dose into 4 XS to Medium doses with just over a Medium dose to spare. That makes it pretty darn cheap for a product that works really well. It is an active infestation, so they are bound to get some fleas here and there and scratch a bit. It comes with the territory. Until the fleas are knocked down outdoors and until their life cycle is broken indoors, there will be fleas. Fighting an indoor flea infestation WILL take 6 weeks or a bit longer. I can't speak for how consistent this product is, as most products can have a dud here and there, but I have serious doubt with regard to all the people giving negative reviews because their dog got a few fleas after this product was applied. I don't know their back story, but fleas don't just sprout from the air and ticks are unlikely to fall off in a day. Odds are they have a yard and/or house full of fleas (just like I'm dealing with) and are expecting this to work miracles. It won't. Also, could be that they applied it to the dog's fur rather than on the dog's skin where it can be adsorbed. First off, CONTROL THE WILD FLEAS. Use an IGR in and around your house, and also get the proper microencapsulated pesticide for your usage case. If you have no cats around, permethrin based is great - like Onslaught Fastcap, Bifen I/T, or whatever indoor bug spray from the local hardware store. Wet down every bit of flooring, every baseboard, every access point. Let it dry before you let anyone/anything back in. Repeat every 2 weeks. If there are cats, use something cat safe like some hippie plant oil based garbage that needs to be applied every few days or do your own research and find an effective product. Get some insecticide granules and a spreader for your lawn. If cats, use Sevin or some hippie formulation (or whatever). If no cats, you have more options including Bifen L/P, Spectracide Triazicide, Talstar PL -- or even a cat-safe hippie formula if you just want use a less effective product and apply it way more often. Always wet the granules down after spreading. There is rarely a magic bullet when you're fighting nature.
A**E
Works great awesome I definitely suggested
UPDATE I don’t know what y’all all your people take your dogs to the vets instead of showing them online here that they can’t walk. The fur is falling out of the bleeding. That’s ridiculous. Take your dog to the friggin neck. Let the vet determine the cause exactly and then if it’s in clause because of this then Put a negative and state the fact that you took him to a vet and the vet did test and it was the closet because I’ve been using this product for 25 years on my dogs back then and my new dogs now my dogs I had 16 years ago dogs I had 10 years ago dogs I had 13 years ago my 16 1/2 year old cocker spaniel has had this from the day he could actually have this And I have never had a problem with that on any of my dogs especially him you know it got rid of the fleas and I noticed a few texts very easy to get off compared when I didn’t use it like if I skipped a couple of months and they had a dick and I was like oh my God and then I would try to get it off and it was a hassle. I mean, it did not pull up. Come out whatever And so I put them back on this every month originally and if they get a tick and I see it. I just need tweezers and it just pops right off no eggs inside nothing no problem with the weather did not cause any of my dogs ever itch or lose hair so I think you people have an undergoing problem with your dog that you did not address Prior to use this. Yes, I’m gonna blame you. Yes I’m blaming all you that people that has undermining problems with their dog and you don’t take them to the vet and you add this product on top of them. Yes, it probably will do something like that. SO I REPEAT, TAKE YOUR DOG TO THE GD VETERINARIAN PROFESSIONAL LET THE PROFESSIONAL DO THEIR WORK !!!! Oh, I also have one dog right now. I have three of them English mastiff and I have one of them that sits at my back gate in the dirt never has fleas never has sticks never has any. He lays in the dirt 185 pound and his head I can look it out right now his head is in it. His whole body lengthwise is in it and I swear he digs holes just you know it makes it cool.. and there’s a picture of him laying at the fence in the dirt. He loves it. I check them every day. Nobody has fleas. Nobody has anything so you people are doing something wrong. I’m gonna blame all of you. They have a problem and I’ll say it again again again they have underlining problem TAKE THEM TO THE VET VETERINARIAN HAVE THE VET, VETERINARIAN, TECHNICIAN, AND DOCTOR EXAMINE THE DOG TAKE SKIN GRAPHS WHATEVER THE BEST HAS TO DO. DON’T BLAME THE PRODUCT UNLESS YOU DID THAT AND IF YOU DID IT AND THEN DOCTOR RUNS TEXT AND SAID YES, IT WAS CAUSED BY THAT PRODUCT. WELL HENCE THERE YOU GO AND IT’S THE PRODUCT FAULT BUT A 99.999% IT’S NOT THE PRODUCT. Started having dogs when we first got married we have we had seven English mastiffs yeah it’s addicting and they had puppies and everything so anyways I’ve been using this on my dogs from year 2000 and I use them before that on my other dog so I’ve always used it really and I love it. I mean, I swear by it this stuff is great. My dogs do not get flea or I mean I have to put a spray on them to detail the mosquitoes, but don’t see my bugs biting them. It’s pricey, but it’s worth it. You don’t wanna have your dogs get Lyme disease or you know from ticks, I really suggest this. No bother my dog knock on wood you know in the other thing is I don’t use this year around. I only use it from spring until after fall. I don’t feel I really needed in the winter time. It’s too cold outside for anything to live so I’m up Northeast And I don’t seem to have any problem and they’re not using it as soon as spring hits that’s that boom they’re on it.
Y**N
The safest and most effective tick protection - ticks fall off just from touching the fur
I brought my dog to West Virginia, and thank God for Advantix II — because I’ve been finding half-dead ticks every single day (no joke) in places where she sleeps or rests. At first, I was confused. I thought "repels ticks" meant it would work like bug spray does for mosquitoes, keeping them away completely. But after looking into the active ingredient, permethrin, I realized that in this case, “repel” means: once a tick touches the treated fur, it becomes so irritated or neurologically impaired that it can’t bite, can’t hang on, and eventually just falls off and dies. That’s still so much better than PetArmor, Frontline, or any of the oral preventatives (like Simparica or NexGard), which require the tick to bite the dog before it dies. No thanks. Every tick I’ve found so far had already dropped off my dog before it had a chance to bite her and feed — exactly what you want in a tick-heavy area. I’ve also tried Wondercide (cedar oil). It works okay for fleas, but it’s just not effective for ticks, especially not in the long term. Its protection wears off after 2–4 hours. I learned the hard way — my dog caught Lyme disease, developed joint pain and a limp. Thankfully, doxycycline helped and she’s okay now, but it required a full 28-day antibiotic course. I would never use oral flea/tick medications. Just ask around — you’ll hear plenty of stories about dogs having seizures after taking them. For me, that risk isn’t worth it. If you have a cat at home, unfortunately Advantix II may not be right for your household — permethrin is toxic to cats (especially when wet). But if you don’t have cats, I highly recommend this product to all dog owners. Tick-borne diseases are no joke. Fleas are annoying — I’ve had to go through the nightmare of clearing an infestation — but at least they just suck blood without causing life-threatening illness. Ticks, on the other hand, can transmit Lyme, Ehrlichia, Rocky Mountain spotted fever, and more. So if you live somewhere warm, humid, grassy, or deer-heavy — do your dog a favor and get Advantix II. It’s been a lifesaver for us.
A**E
Good
It actually works better than I thought. My dog went from scratching and bitting constantly to every now and then. Still see a flea occasionally but nothing like before I used it. Easy to apply. No for. Not sure that it last the full 30 days but I’ll take 20!
C**L
Great flea and tick medicine
Works good. No bugs on my dog. Good price? No hair loss, no odor, no side effects, durable
M**R
Total waste of money
My dogs were on this medication for months and months and months. If anything the fleas got worse. I can vouch for these not doing a damn thing. My poor dogs suffered for months. I'll go to the vet and get a much better working product for probably the same price.
T**L
Works
Works great on our 3 dogs. Worth the subscription
U**A
Does Not Provide Correct Dosage
Always curious as to why some products work and others do not and decided to test it. Purchased for an Extra Large Dog (75 lbs), which requires a dose of 4.0 ml. Was not working properly, so I purchased a test vial and syringe. Actually amount received in XLarge was 3.5 ml (give or take .1 ml). Not sure how much of a difference this makes for effectiveness but my small breed dog (8 lbs) only gets the .04 ml dosage and has no issues. I am not a scientist but based on recommended dosage, the larger the dog the more medicine required. However, it is not simple math. A 10 lb dog gets .04 ml but a 11-20 gets 1.0 (not .08). Every increase in 10 lbs adds an additional .05 ml, so a 50 lb dog would get 2.5 ml. So, using rough math (not science) an 80 lb dog would need approximately 4.0 ml, which is their max dose (they do not offer a giant dose as 4.0 is suppose to be good for 55+ lbs). However, my gripe is that the XLarge Breed tubes do not even contain the necessary 4.0 ml so how can they be truly effective? Also, if you have a Giant Breed, is it going to be effective beyond 80lbs? As consumers, we do not know what we are actually getting in these tubes and if we are getting what we paid for. Not only that but why does it cost me the same price for .04 ml as 4.0 ml? Yes, I can break up a large tube and use on multiple dogs (which makes economical sense) but would it not make more sense to simply charge based on the amount of medication being provided? So, for those purchasing going forward, this is an effective product but would be smart to buy the glass vials and blunt syringes and simply self dose based on the .05 per 10 lbs (or .025 per 5 lbs). For a small dog, you could use 1 XLarge tube for the entire season (with extra depending on size). I have found this to be effective. Additionally, if you are like me with a large and small breed, you can ensure both dogs are getting the correct dosage. As such, I have to open 2 tubes and dose she small with .05 ml and ensure the large is getting the full 4.0 ml, then save the remainder for the following month (usually around 2.5 - 3.0 ml). I then open a new tube and repeat the process. This has been successful for me.
R**F
No es el producto que se anuncia!
No es el producto de la foto ni de la descripción. Es el Advantix normal, el de la caja azul, nada de k9 ni versión 2.. es contra 4 tipos de insectos y no contra 8 .. Lo compré por qué supuestamente era la versión ii Me siento engañado, no lo devolví por qué me iba de viaje y necesitaba echarle algo ya, si no lo habría devuelto.
S**N
No vino en su caja original
Vino tarde y y no en la caja original si que traía instrucciones, pero además tarde
Trustpilot
1 week ago
2 months ago