---
product_id: 720262145
title: "M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack"
brand: "apagard"
price: "7235 som"
currency: KGS
in_stock: true
reviews_count: 8
category: "Apagard"
url: https://www.desertcart.kg/products/720262145-m-plus-sangis-nano-hydroxyapatite-toothpaste-for-naturally-whiter-teeth
store_origin: KG
region: Kyrgyzstan
---

# Fluoride-free natural formula Nano-Hydroxyapatite enamel repair Family-sized 130g tube M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack

**Brand:** apagard
**Price:** 7235 som
**Availability:** ✅ In Stock

## Summary

> 🦷 Elevate your smile game with Japan’s nano-tech whitening powerhouse!

## Quick Answers

- **What is this?** M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack by apagard
- **How much does it cost?** 7235 som with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.kg](https://www.desertcart.kg/products/720262145-m-plus-sangis-nano-hydroxyapatite-toothpaste-for-naturally-whiter-teeth)

## Best For

- apagard enthusiasts

## Why This Product

- Trusted apagard brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Sensitivity Savior:** Trusted by users worldwide to dramatically reduce tooth sensitivity and improve gum comfort with consistent use.
- • **All-Age Family Formula:** Generous 130g size designed for the whole family’s oral care routine, blending whitening and gum health.
- • **Plaque & Stain Control:** Clinically proven to remove surface plaque and everyday stains for a brighter, confident smile.
- • **Fluoride-Free Freshness:** Gentle, mild mint flavor with no fluoride—perfect for health-conscious users seeking a clean, natural smile.
- • **Revolutionary Enamel Repair:** Harnesses Japan’s patented nano-Hydroxyapatite to rebuild and strengthen tooth enamel naturally.

## Overview

APAGARD® M-Plus is a fluoride-free toothpaste featuring Sangi’s original nano-Hydroxyapatite, a cutting-edge enamel-repair ingredient pioneered in Japan. This 130g family-sized tube offers a mild mint flavor and delivers effective plaque removal, stain control, and sensitivity relief. Ideal for all ages, it supports natural whitening and gum health through consistent, gentle brushing—making it a must-have for professionals who demand both science-backed results and a fresh, confident smile.

## Description

Ingredients (INCI name): DICALCIUM PHOSPHATE, AQUA, GLYCERIN, SILICA, HYDROXYAPATITE, PEG-8, SODIUM LAURYL SULFATE, CELLULOSE GUM, AROMA, TRIMAGNESIUM PHOSPHATE, PVP, HYDROLYZED CONCHIOLIN PROTEIN, SODIUM SACCHARIN, GLYCYRRHETINIC ACID, CETYLPYRIDINIUM CHLORIDE, LAURYL DIETHYLENEDIAMINOGLYCINE HCL

Review: Excellent toothpaste - Best toothpaste I have ever used to date. There are several toothpastes that whiten your teeth, help prevent plaque build up, improve gum health, reduce sensitivity, strengthen enamel, even claim to remove tartar ( slowly ). To say that the market is overhyped is putting it mildly. There are toothpastes made with neem (excellent at keeping plaque at bay, xylitol which prevents the bio film from sticking. Every kind of fluoride ( Sodium fluoride, sodium mono fluoro phosphate, stannous fluoride ….). Then there are toothpastes for tooth sensitivity ( potassium nitrate or arginine bicarbonate ). Now for those of use that prefer to use a toothpaste which does not contain a fluoride, there are the nano hydroxy apatite versions. As expected there are a range of claims and each has its adherents. I suffered for several weeks following the fitting of 2 crowns from a very unusual pain / feeling of tightness in my gums. Tried just about every toothpaste and mouthwash ( including chlorhexidine ). Nothing seemed to help until I tried Boka nano hydroxy toothpaste. Within 2 days I noticed a difference. Then I learnt of the Apgard M plus and the premio. I tried the M plus and noticed that the rate of improvement in my gum issue accelerated. Look I know there are all kinds of claims and counterclaims. You need at least 10% nano hydroxy apatite. The size and shape of the nanoparticle matters. Some claim SLS and other additives are unwanted, others say they are best present to create foam … The bottom line M plus in its current form is been in production since 1985. The Japanese manufacturer bought out the original NASA patent. It works. By far the best I have experienced for tooth sensitivity, gum health, keeping the enamel free of plaque. Is it as good as the premio or higher versions. I don’t know, I have never tried them. This version works well. Brush your teeth twice a day at least for at least 2-3 minutes, rinse lightly and spit out. Are there other equivalent or better options out there. ( Dr Jens, Ollie, … ) very possibly. All I can say is that I never expected a toothpaste to have such noticeable improvements on my teeth and gums. To me the fact that it’s made by the Japanese who are known for quality and reproducible process control, is a plus. I am satisfied.
Review: Game Changer for Sensitive Teeth - I’ve purchased this multiple times and it’s still my absolute favorite toothpaste. I struggle with pretty intense tooth sensitivity, and this is honestly the only toothpaste I’ve ever tried that makes such a dramatic difference. It took my hyper-sensitive teeth to hardly feeling sensitive at all. The key for me has been using it consistently—I noticed a real improvement about halfway through my first tube. I typically brush, then do a very light rinse and avoid rinsing around my teeth so the paste can keep working. It also leaves my mouth feeling super fresh and clean. After finishing Invisalign, I had a huge spike in sensitivity and this helped resolve it more than anything else. Highly recommend if you deal with sensitive teeth!

## Features

- Japan’s Leading Hydroxyapatite Toothpaste is now in the US. APAGARD features Sangi’s original nano-Hydroxyapatite (nano-mHAP), delivering Japan’s ground-breaking oral care expertise to your daily routine.
- Cleans Teeth & Helps Remove Surface Plaque. With consistent brushing, APAGARD nano-Hydroxyapatite toothpaste helps remove plaque and everyday stains, giving you a naturally brighter smile.
- APAGARD M-plus is the standard, classic version and longest-selling product in the APAGARD range. It offers an all-around balance between natural whiteness enhancement, breath care, and stain control, and is suited for all ages, coming in a higher volume package ideal for family use.
- Contains SANGI's Original nano-Hydroxyapatite -the building block of tooth enamel- , which was first synthesized by SANGI Co.,Ltd in 1978.
- For optimal effect from your nano-mHAP toothpaste, we recommend that you (1) Place a small amount (1-1.5 cm/ 0.4-0.6 inch) on a toothbrush. (2) Brush your teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal (3 times/ day is recommended). (3)Rinse lightly and spit out after brushing, avoiding excessive rinsing.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0F1FMTJXR |
| Age Range (Description) | All Ages |
| Age Range Description | All Ages |
| Best Sellers Rank | #23,120 in Health & Household ( See Top 100 in Health & Household ) #344 in Toothpaste |
| Brand | APAGARD |
| Brand Name | APAGARD |
| Capacity | 135 Milliliters |
| Customer Reviews | 4.6 out of 5 stars 97 Reviews |
| Flavor | Mild Mint |
| Item Form | Paste |
| Manufacturer | SANGI CO.,LTD |
| Material Feature | Natural |
| Material Features | Natural |
| Number of Items | 1 |
| Product Benefits | Whitening |
| Target Audience | Unisex-Adults |
| Unit Count | 4.58 Ounce |

## Product Details

- **Age Range (Description):** All Ages
- **Brand:** APAGARD
- **Flavor:** Mild Mint
- **Item Form:** Paste
- **Material Feature:** Natural

## Images

![M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth. Fluoride-Free, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Single Pack - Image 1](https://m.media-amazon.com/images/I/61DmvslT4YL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Excellent toothpaste
*by N***E on October 14, 2025*

Best toothpaste I have ever used to date. There are several toothpastes that whiten your teeth, help prevent plaque build up, improve gum health, reduce sensitivity, strengthen enamel, even claim to remove tartar ( slowly ). To say that the market is overhyped is putting it mildly. There are toothpastes made with neem (excellent at keeping plaque at bay, xylitol which prevents the bio film from sticking. Every kind of fluoride ( Sodium fluoride, sodium mono fluoro phosphate, stannous fluoride ….). Then there are toothpastes for tooth sensitivity ( potassium nitrate or arginine bicarbonate ). Now for those of use that prefer to use a toothpaste which does not contain a fluoride, there are the nano hydroxy apatite versions. As expected there are a range of claims and each has its adherents. I suffered for several weeks following the fitting of 2 crowns from a very unusual pain / feeling of tightness in my gums. Tried just about every toothpaste and mouthwash ( including chlorhexidine ). Nothing seemed to help until I tried Boka nano hydroxy toothpaste. Within 2 days I noticed a difference. Then I learnt of the Apgard M plus and the premio. I tried the M plus and noticed that the rate of improvement in my gum issue accelerated. Look I know there are all kinds of claims and counterclaims. You need at least 10% nano hydroxy apatite. The size and shape of the nanoparticle matters. Some claim SLS and other additives are unwanted, others say they are best present to create foam … The bottom line M plus in its current form is been in production since 1985. The Japanese manufacturer bought out the original NASA patent. It works. By far the best I have experienced for tooth sensitivity, gum health, keeping the enamel free of plaque. Is it as good as the premio or higher versions. I don’t know, I have never tried them. This version works well. Brush your teeth twice a day at least for at least 2-3 minutes, rinse lightly and spit out. Are there other equivalent or better options out there. ( Dr Jens, Ollie, … ) very possibly. All I can say is that I never expected a toothpaste to have such noticeable improvements on my teeth and gums. To me the fact that it’s made by the Japanese who are known for quality and reproducible process control, is a plus. I am satisfied.

### ⭐⭐⭐⭐⭐ Game Changer for Sensitive Teeth
*by E***S on January 14, 2026*

I’ve purchased this multiple times and it’s still my absolute favorite toothpaste. I struggle with pretty intense tooth sensitivity, and this is honestly the only toothpaste I’ve ever tried that makes such a dramatic difference. It took my hyper-sensitive teeth to hardly feeling sensitive at all. The key for me has been using it consistently—I noticed a real improvement about halfway through my first tube. I typically brush, then do a very light rinse and avoid rinsing around my teeth so the paste can keep working. It also leaves my mouth feeling super fresh and clean. After finishing Invisalign, I had a huge spike in sensitivity and this helped resolve it more than anything else. Highly recommend if you deal with sensitive teeth!

### ⭐⭐⭐⭐⭐ Decent premium toothpaste
*by P***S on November 19, 2025*

I’ve been using this stuff for a couple of years now. I’m not sure how effective it is in preventing cavities or healing my teeth, but it makes me feel good and it doesn’t have any fluoride in it and it tastes pretty good. Better safe than sorry and this is a good deal for two tubes of toothpaste.

## Frequently Bought Together

- APAGARD® M-Plus, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, for Family use, 130g / 4.58 oz, Mild Mint Flavor, Pack of 1
- Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured
- Apagard Tooth Polish Royal 135g toothpaste, Direct from Japan

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*Product available on Desertcart Kyrgyzstan*
*Store origin: KG*
*Last updated: 2026-03-08*